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Medical Writing and Professional Training Is to publish the results of original experimental research that contribute significantly to knowledge in medical and biological sciences. Major criteria for acceptance are scientific quality, originality, and conciseness. Preference will be given to manuscripts that develop new concepts or experimental approaches and are not merely repositories of data. Papers that report negative results require special justification for publication. Methodological papers shall be considered for publication provided they describe new principles or a significant improvement of an existing method. The following papers will not be accepted for publication publishes original research articles of outstanding scientific significance. We will consider manuscripts of any length; we encourage the submission of both substantial full-length bodies of work and shorter manuscripts that report novel findings that might be based on a limited number of experiments. The key criteria are that the research clearly demonstrates its novelty, its importance to a particular field as well as its interest to those outside that discipline, and conclusions that are justified by the data. Authorship requirements Only those persons who contributed directly to the intellectual content of the paper should be listed as authors. Authors should meet all of the following criteria, thereby allowing persons named as authors to take public responsibility for the content of the paper. follows the reference format of the Uniform Requirements for Manuscripts Submitted to Biomedical Journals, which can be found on the website of the National Library of Medicine ( The writing style should be concise and accessible. Editors will make suggestions for how to achieve this, as well as suggestions for cuts or additions that could be made to the article to strengthen the argument. Our aim is to make the editorial process rigorous and consistent, but not intrusive or overbearing. Authors are encouraged to use their own voice and to decide how best to present their ideas, results, and conclusions. Although we encourage submissions from around the globe, we require that manuscripts be submitted in American English. As a step towards overcoming language barriers, we encourage authors to seek the assistance of professional services available on the homepage of the journal/Service and Information. Footnotes Text footnotes, if unavoidable, should be numbered consecutively in superscript in the manuscript and written on a separate page following the abstract. Abbreviations Abbreviations should be kept to a minimum. Define all abbreviations upon first use in the abstract and the text. Non-standard abbreviations should not be used unless they appear at least three times in the text. Nomenclature v The use of standardized nomenclature in all fields of science and medicine is an essential step toward the integration and linking of scientific information reported in published literature. We will enforce the use of correct and established nomenclature wherever possible: We strongly encourage the use of SI units. ), genes, mutations, genotypes, and alleles should be italicized. Use the recommended name by consulting the appropriate genetic nomenclature database, e.g., HUGO for human genes. It is sometimes advisable to indicate the synonyms for the gene the first time it appears in the text. The Recommended International Non-Proprietary Name (r INN) of drugs should be provided. Authors should state in the cover letter that the manuscript is intended to be a Full-length Paper, Short Communication, Review Article, Overview, Concepts and Comments, or Case Report. Full-length paper Each manuscript should clearly state its objective or hypothesis; the experimental design and methods used (including the study setting and time period, patients or participants with inclusion and exclusion criteria, or data sources and how these were selected for the study); the essential features of any interventions; the main outcome measures; the main results of the study; and a discussion placing the results in the context of published literature. The manuscript should contain: Short communication A short communication is a report on a single subject, which should be concise but definitive. The scope of this section is intended to be wide and to encompass methodology and experimental data on subjects of interest to the readers of the Journal. The manuscript should contain: Review article A review article should provide a synthetic and critical analysis of a relevant area and should not be merely a chronological description of the literature. A review article by investigators who have made substantial contributions to a specific area in medical and biological sciences will be published by invitation of the Editors. However, an outline of a review article may be submitted to the Editors without prior consultation. If it is judged appropriate for the Journal, the author(s) will be invited to prepare the article for peer review. A minireview is focused on a restricted part of a subject normally covered in a review article. The manuscript should contain: Overview An overview does not contain unpublished data. It presents the point of view of the author(s) in a less rigorous form than in a regular review or minireview and is of interest to the general reader. The manuscript should contain: Most articles published in the Brazilian Journal of Medical and Biological Research will be organized into the following sections: Title, Authors, Affiliations, Abstract, Key words, Running Title, Author for Correspondence and email address Introduction Material and Methods Results Discussion Acknowledgments References Tables with a short descriptive title and footnote legends Figures with a short descriptive title, descriptive legends and uniformity in format Continuous page numbers are required for all pages including figures. There are no specific length restrictions for the overall manuscript or individual sections. However, we urge authors to present and discuss their findings concisely. We recognize that some articles will not be best presented in our research article format. If you have a manuscript that would benefit from a different format, please contact the editors to discuss this further. Title Page Title - The title should be as short and informative as possible, should not contain non-standard acronyms or abbreviations, and should not exceed two printed lines. Example: Single-step purification of crotapotin and crotactine from Crotalus durissus terrificus venom using preparative isoelectric focusing Authors and Affiliations Initials and last name(s) of author(s) (matched with superscript numbers identifying institutions). Aguiar Departamento de Biologia Celular e Molecular, Universidade Federal Fluminense, Niterói, RJ, Brasil Abstract Since abstracts are published separately by Information Services, they should contain sufficient hard data, to be appreciated by the reader. Institution(s) (Department, Faculty, University, City, State, Country) of each author (in Portuguese if authors are from Brazil). The Brazilian Journal publishes unstructured abstracts in a single paragraph. The abstract should briefly and clearly present the objective, experimental approach, new results as quantitative data if possible, and conclusions. It should mention the techniques used without going into methodological detail and mention the most important results. Abbreviations should be kept to a minimum and should be defined in both the Abstract and text. Please do not include any reference citations in the abstract. If the use of a reference is unavoidable, the full citation should be given within the abstract. Please see for suggestions on writing a good abstract Key Words A list of key words or indexing terms (no more than 6) should be included. A capital letter should be used for the first letter of each key word, separated by a semicolon. The Journal recommends the use of medical subject headings of Index Medicus for key words to avoid the use of several synonyms as entry terms in the index for different papers on the same subject. Remember, key words are used by the Scielo Database (see search/subject) to index published articles. Running title This short title, to be used as a page heading, should not exceed 60 letters and spaces. Corresponding author One of the authors should be designated as the corresponding author. It is the corresponding authors responsibility to ensure that the author list is accurate and complete. If the article has been submitted on behalf of a consortium, all consortium members and affiliations should be listed in the Acknowledgments section. Provide the name and email address of the author to whom correspondence should be sent. Introduction The Introduction should put the focus of the manuscript into a broader context. As you compose the Introduction, think of readers who are not experts in this field. This should state the purpose of the investigation and justification for undertaking the research and relationship to other work in the field. An extensive listing or review of the literature should not be used. If there are relevant controversies or disagreements in the field, they should be mentioned so that a non-expert reader can delve into these issues further. The Introduction should conclude with a brief statement of the overall aim of the experiments and a comment about what was achieved. Material and Methods Sufficient information should be provided in the text or by referring to papers in generally available journals to permit the work to be repeated. This section should provide enough detail for reproduction of the findings. Protocols for new methods should be included, but well-established protocols may simply be referenced. We encourage authors to submit, as separate files, detailed protocols for newer or less well-established methods. These will be linked to the article and will be fully accessable. Results The results should be presented clearly and concisely. Tables and figures should be used only when necessary for effective comprehension of the data. The Results section should provide results of all of the experiments that are required to support the conclusions of the paper. There is no specific word limit for this section, but a description of experiments that are peripheral to the main message of the article and that detract from the focus of the article should not be included. The section may be divided into subsections, each with a concise subheading. Large datasets, including raw data, should be submitted as supplementary files; these are published online linked to the article. The Results section should be written in past tense. In some situations, it may be desirable to combine Results and Discussion into a single section. Discussion The purpose of the Discussion is to identify new and relevant results and relate them to existing knowledge. Information given elsewhere in the text, especially in Results, may be cited but all of the results should not be repeated in detail in the Discussion. The Discussion should spell out the major conclusions and interpretations of the work including some explanation of the significance of these conclusions. How do the conclusions affect the existing assumptions and models in the field? How can future research build on these observations? The Discussion should be concise and tightly argued. If warranted, the Results and Discussion may be combined into one section. Acknowledgments When appropriate, briefly acknowledge technical assistance, advice and contributions from colleagues. People who contributed to the work, but do not fit the criteria for authors should be listed in the Acknowledgments section, along with their contributions. Donations of animals, cells, or reagents should also be acknowledged You must also ensure that anyone named in the Acknowledgments agrees to being so named. Financial support for the research and fellowships should be acknowledged in this section (agency and grant number). Figures Figures must be submitted in high-resolution version (600 dpi). Please ensure that the files conform to our Guidelines for Figure Preparation when preparing your figures for production and/or "Image Quality Specifications". The link contains important information about image quality from Pub Med Central where the Brazilian Journal of Medical and Biological Research is indexed. The Brazilian Journal of Medical and Biological Research requires the same quality as Pub Med Central. Please follow these instructions when you submit figures to the Brazilian Journal. "Unpublished results", "Personal communication" and "Submitted papers". Preparing figure files for submission The Brazilian Journal of Medical and Biological Research encourages authors to use figures where this will increase the clarity of an article. The use of water quality modelling for optimising operation of a drinking water reservoir. Reference should appear in the text with the individual name(s) and initials and not in the reference list. The use of color figures in articles is free of charge. Proceedings of the International Conference Fluid Mechanics and Hydrology. (Santos CS, da-Silva GB, Martins LT, unpublished results). The following guidelines must be observed when preparing figures. It is assumed that the author has obtained permission from the source when "personal communication" is cited. Failure to do so is likely to delay acceptance and publication of the article. Author Instructions Please make sure you have read through these instructions carefully before beginning the submission process. Please note that it is the responsibility of the author(s) to obtain permission from the copyright holder to reproduce figures (or tables) that have previously been published elsewhere. Visão no ultravioleta em Carassius auratus (Ostariophysi, Cypriformes, Cyprinidae): estudo eletrofisiológico do sistema cone - células horizontais. Please go to at the right-hand corner of the home page and click on SUBMIT A MANUSCRIPT and follow the directions. In order for all figures to be open-access, authors must have permission from the rights holder if they wish to include images that have been published elsewhere in non-open-access journals. Global strategy for asthma management and prevention: NHLBI/WHO Workshop Report. National Heart, Lung and Blood Institute publication No. If you need further assistance, please contact the Journal Staff directly ([email protected]). Permission should be indicated in the figure legend, and the original source included in the reference list. Manuscript preparation instructions can be found at Supported file type The following file format can be accepted: TIFF (suitable for images) with 600 dpi. Submission Process The seven steps of the submission process are: Type, Title & Abstract; Attributes; Authors & Institutions; Recommended Reviewers; Details & Comments; File upload; Review & Submit. Micrographs should be treated like photographs with the following additional guidelines Tables References Only published or accepted manuscripts should be included in the reference list. The steps each contain sub-steps that can be accessed by clicking on their respective tabs. Meeting abstracts, conference talks, or papers that have been submitted but not yet accepted should not be cited. The Brazilian Journal of Medical and Biological Research is a peer-reviewed electronic journal published monthly by the Associação Brasileira de Divulgação Científica (ABDC). Limited citation of unpublished work should be included in the body of the text only. Report WHO (World Health Organization), IPCS (International Program in Chemical Safety). Submission of a manuscript to the Brazilian Journal implies that the data have not been published previously and will not be submitted for publication elsewhere while the manuscript is under review. All personal communications should be supported by a letter from the relevant authors. In: Kintzios SE, Barberaki MG (Editors), Plants that fight cancer. Environmental health criteria: 118 Inorganic mercury. The following represent "prior publication": any printed material in excess of 500 words describing results or methods of a submitted/in press manuscript; published tables or illustrations that duplicate the content of a manuscript; electronic manuscripts or posters available via the Internet. Authors are responsible for the accuracy and completeness of their references and for correct text citation. When part of the material in a manuscript has been presented as a preliminary communication or in an unrefereed symposium, this should be cited as a footnote on the title page and a copy should accompany the submitted manuscript. When possible, references which are easily available in English should be cited. Authors, Chapter Title, Editors, Book title, Edition, City, Publisher, Year, Pages of citation. Behavioral effects of cytokines: a psychiatrist's perspective. The Brazilian Journal of Medical and Biological Research (BJMBR) applies the Creative Commons Attribution License (CCAL) to all works published (read the human-readable summary or the full license legal code). The BJMBR uses the numbered citation (citation-sequence) method. Authors, Book title, Edition, City, Publisher, Year. Diretrizes do ACSM para os testes de esforço e sua prescrição. In: Plotnikoff NP, Faith RE, Murgo AJ, Good RA (Editors), Cytokines, stress and immunity. Under the CCAL, authors retain ownership of the copyright for their article and can allow anyone to download, reuse, reprint, modify, distribute, and/or copy articles published in the BJMBR, as long as the original authors and source are cited. The main characteristic of research papers in the area of Cell Biology is the emphasis on the integration at the cellular level of biochemical, molecular, genetic, physiological, and pathological information. References are listed and numbered in the order that they appear in the text. This section considers manuscripts dealing with either prokaryotic or eukaryotic biological systems at any developmental stage. In the text, citations should be indicated by the reference number in parentheses. Computer Program Dean AG, Dean JA, Coulombier D, Brendel KA, Smith DC, Burton AH, et al. Papers on all aspects of cellular structure and function are considered to be within the scope of Cell Biology by the BJMBR. Multiple citations within a single set of parentheses should be separated by commas without a space (1,5,7) . Epi info, version 6.04: a word processing database and statistics program for public health on IBM-compatible microcomputers. Atlanta: Centers of Disease Control and Prevention; 1998. Methods for procedures related to the electrophysiology of the heart. The Editors encourage submission of manuscripts defining cell biology as an area of convergence of several other research fields, especially manuscripts providing insights into the cellular basis of immunology, neurobiology, microbial pathology, developmental biology, and disease. Where there are 3 or more sequential citations, they should be given as a range (4-9). Manuscripts containing purely descriptive observations will not be published. Because all references will be linked electronically (doi), if possible, to the papers they cite, proper formatting of the references is crucial. Audiovisual Material Physician's Desk Reference (PDR). Manuscripts reporting new techniques will be published only when adequately validated and judged by the Editors to represent a significant advance. For all references, list the first 6 authors followed by et al., Title of article, Journal (abbreviation), Year, Volume, Complete Pages, The Brazilian Journal of Medical and Biological Research follows the reference format of the Uniform Requirements for Manuscripts Submitted to Biomedical Journals, which can be found on the website of the National Library of Medicine ( CNPq Plataforma Lattes, "Investimentos do CNPq em CT&I". The receipt of manuscripts is acknowledged immediately. Use the Medline journal abbreviations and follow the reference style shown on the Website noted above, with several exceptions. If the author uses the program "Reference Manager", copy the file containing the style of the Brazilian Journal of Medical and Biological Research and place it in the folder of "Styles". Once a paper has been evaluated by peer review, the authors will be notified of the editorial decision. When submiting the manuscript, send the file produced in Reference Manager (".rmd" and ".rmx" ) as an attachment. Papers accepted on scientific merit for publication sent to authors for scientific english correction and galley proofs will be sent to authors for the correction of errors. Please use the following style for the reference list: Published Papers. Authors are responsible for all statements made in their article, including changes made by the copy editor and authorized by the corresponding author. First 6 authors followed by et al., Title, Journal (abbreviation in italics), Year, Volume, Complete Pages. The 6-minute walk test: normal values for children of 4-11 years of age. Zhang Q, Malik P, Pandey D, Gupta S, Jagnandan D, Belin de CE, et al. The dates of receipt and acceptance will be published for each article. Paradoxical activation of endothelial nitric oxide synthase by NADPH oxidase. Article accepted for publication but not yet published. Authors are expected to return manuscripts to the Journal within 15 calendar days after they are sent to them for modifications or for style and copy editing, and to return galley proofs within 72 hours. First 6 authors followed by et al., Title, Journal (abbreviation), Year of expected publication, (in press) at the end of the citation. The total number of "late" days will be added to the submission date at the time of publication. Janiszewski M, Lopes LR, Carmo AO, Pedro MA, Brandes RP, Santos CXC, et al. Regulation of NAD(P)H oxidase by associated protein disulfide isomerase in vascular smooth muscle cells.2005 (in press). AdRes supplies a critical literature review service for cal reports and paper. 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